Sergeev P V, Mashkovtsev Iu V, Obratsov N V
Farmakol Toksikol. 1980 Mar-Apr;43(2):180-4.
Electron microscopic studies on rats have shown that promptly (30 sec--5 min) after administration to the portal vein, bilignost progresses diffusely, through the cell membrane, from Disse's space and intercellular slits to the hepatocytic cytoplasm. It is accumulated by the cytoplasm and subcellular organellas and then is rapidly eliminated from the cells to bile capillaries.
对大鼠的电子显微镜研究表明，必利胆醇经门静脉给药后迅速（30秒至5分钟）在肝内广泛扩散，穿过细胞膜，从狄氏间隙和细胞间缝隙进入肝细胞质。它被细胞质和亚细胞器摄取，然后迅速从细胞中排入胆小管。
