K99表面抗原的生物合成受到丙氨酸的抑制。
Biosynthesis of the K99 surface antigen is repressed by alanine.
作者信息
de Graaf F K, Klaasen-Boor P, van Hees J E
出版信息
Infect Immun. 1980 Oct;30(1):125-8. doi: 10.1128/iai.30.1.125-128.1980.
Abstract
The amino acid alanine induced a direct and specific repression of the biosynthesis of the K99 surface antigen in Escherichia coli strains harboring the K99 plasmid. In minimal medium with 0.5% glucose, 1 mM L-alanine was sufficient to reduce the K99 production by about 95%. The low production of the K99 antigen by strains growing on commercially available nutrient media seemed to be a result of the inhibitory effect alanine on the K99 biosynthesis.
摘要
氨基酸丙氨酸可直接特异性抑制携带K99质粒的大肠杆菌菌株中K99表面抗原的生物合成。在含有0.5%葡萄糖的基本培养基中，1 mM L-丙氨酸足以使K99的产量降低约95%。在市售营养培养基上生长的菌株中K99抗原产量较低，这似乎是丙氨酸对K99生物合成的抑制作用所致。
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本文引用的文献
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