Bäck E, Möllby R, Kaijser B, Stintzing G, Wadström T, Habte D
J Infect Dis. 1980 Sep;142(3):318-27. doi: 10.1093/infdis/142.3.318.
Heat-labile enterotoxin (LT)-producing Escherichia coli and other enteric bacteria isolated from diarrheal Ethiopian children were studied for O and K antigen, production of heat-stable enterotoxin (ST), stability of LT production, properties of mannose-resistant hemagglutination (MRHA) (indicative of adhesive properties), and colonization factor antigen (CFA). Of the E. coli strains, 33% possessed O6, O8, or O78; 93% of these were stable producers of LT, and 86% produced both Lt and ST. O78 strains possessed CFA/I, whereas O6 and O8 strains possessed CFA/II. The E. coli with O antigens other than O6, O8, or O78, as well as the non-E. coli bacteria tended to lose their ability to produce LT; only 16% produced ST, and they only occasionally showed MRHA properties. The former group of E. coli strains might be considered as true enteropathogenic bacteria (enterovirulent E. coli), which may be identified serologically, while the pathogenic significance of the diversified latter group remains less certain.
对从腹泻的埃塞俄比亚儿童中分离出的产热不稳定肠毒素（LT）的大肠杆菌及其他肠道细菌进行了研究，分析其O抗原和K抗原、热稳定肠毒素（ST）的产生、LT产生的稳定性、甘露糖抗性血凝（MRHA）特性（表明黏附特性）以及定植因子抗原（CFA）。在大肠杆菌菌株中，33%具有O6、O8或O78；其中93%是LT的稳定生产者，86%同时产生LT和ST。O78菌株具有CFA/I，而O6和O8菌株具有CFA/II。具有O6、O8或O78以外O抗原的大肠杆菌以及非大肠杆菌细菌往往会丧失产生LT的能力；只有16%产生ST，且它们只是偶尔表现出MRHA特性。前一组大肠杆菌菌株可被视为真正的肠道病原菌（肠道毒性大肠杆菌），可通过血清学进行鉴定，而后一组多样化细菌的致病意义仍不太明确。
