鼠伤寒沙门氏菌中赋予对5-氟尿嘧啶条件抗性和生物能量缺陷的突变：cad的定位
A mutation in Salmonella typhimurium imparting conditional resistance to 5-fluorouracil and a bioenergetic defect: mapping of cad.
作者信息
Kelln R A, Zak V L
出版信息
Mol Gen Genet. 1980;179(3):677-81. doi: 10.1007/BF00271757.
PMID:7003303
Abstract
The position of the genetic locus allelic with the cad-2 mutation has been located between units 14 and 15 of the linkage map of S. typhimurium. Fine structure mapping established the gene order as cad flrB nag. The genetic evidence coupled with biochemical evidence indicates that this cad locus is homologous to the ubiF gene of Escherichia coli.
摘要
与cad - 2突变等位的基因座在鼠伤寒沙门氏菌连锁图的14和15单位之间定位。精细结构作图确定基因顺序为cad flrB nag。遗传证据与生化证据表明，这个cad基因座与大肠杆菌的ubiF基因同源。
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2
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