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[实验性应激性胃溃疡大白鼠的胃分泌]

[Gastric secretion of white rats with an experimental stress stomach ulcer].

作者信息

Zherev S

出版信息

Probl Khig. 1980;8:47-54.

PMID:7003588
Abstract

The quantity of gastric juice, its acidity and enzymophoretic proteolytic fractions are evaluated in white rats with experimentally induced gastric stress ulcer. Stress ulcer in rats is caused by immobilization and cooling at 0 to 4 degrees C for a duration two hours. It is established that rats with experimental stress ulcers release an increased amount of gastric juice with normal acidity. In the gastric juice of healthy rats a proteolytic fraction is discovered, while in rats with experimentally induced stress ulcer of the stomach two and occasionally three proteolytic induced stress ulcer of the stomach two and occasionally three proteolytic fractions are found. In the discussion due consideration is given to the fact that some of the pathological fractions may play a certain causative role in the formation of gastric ulcers.

摘要

对实验性诱导胃应激性溃疡的白鼠的胃液量、酸度及酶电泳蛋白水解组分进行评估。大鼠的应激性溃疡是通过固定并在0至4摄氏度下冷却两小时诱发的。已证实,患有实验性应激性溃疡的大鼠会分泌出酸度正常但量增加的胃液。在健康大鼠的胃液中发现了一种蛋白水解组分,而在实验性诱发胃应激性溃疡的大鼠中发现了两种,偶尔为三种蛋白水解组分。在讨论中适当考虑了这样一个事实,即某些病理性组分可能在胃溃疡的形成中起一定的致病作用。

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