Galil-Ogly G A, Poroshin K K, Alipchenko L A, Krylov L M
Arkh Patol. 1980;42(11):6-16.
The paper presents detailed morphological characteristics of 31 thymomas and 25 microscopically similar neoplasias of the anterior mediastinum (carcinoid, seminoma, lymphogranulomatosis, angiofollicular lymphoma, etc). The term "thymoma" is determined as a tumour consisting of two components: mandatory epithelial one and lymphocytes. The diversity of the morphological picture of thymomas is determined mainly by the variability of the epithelial component. The special features of the ultrastructural organization of thymomas (the presence of desmosomes, tonofibrils and basal membrane) were revealed which facilitate the differential diagnosis of the anterior mediastinum tumours.
本文介绍了31例胸腺瘤及25例显微镜下与胸腺瘤相似的前纵隔肿瘤(类癌、精原细胞瘤、淋巴肉芽肿病、血管滤泡性淋巴瘤等)的详细形态学特征。“胸腺瘤”这一术语被定义为由两种成分组成的肿瘤:必不可少的上皮成分和淋巴细胞。胸腺瘤形态学表现的多样性主要由上皮成分的变异性决定。揭示了胸腺瘤超微结构组织的特点(存在桥粒、张力原纤维和基底膜),这有助于前纵隔肿瘤的鉴别诊断。