Dodson M E, Fryer J M
Br J Anaesth. 1980 Dec;52(12):1265-70. doi: 10.1093/bja/52.12.1265.
A double-blind study is described in which the analgesic and analeptic properties of methylphenidate were investigated in 63 patients following surgery. No effect of methylphenidate on postoperative pain was observed. However, methylphenidate reduced sedation up to 30 min after operation, and improved respiratory function up to 180 min in patients receiving halothane. No conclusive evidence of improvement in mood was obtained, and occasional undesirable behavioural effects of methylphenidate were seen.
描述了一项双盲研究，其中对63例术后患者的哌甲酯的镇痛和兴奋特性进行了研究。未观察到哌甲酯对术后疼痛有影响。然而，哌甲酯可减轻术后30分钟内的镇静作用，并在接受氟烷的患者中改善呼吸功能长达180分钟。未获得情绪改善的确凿证据，且观察到哌甲酯偶尔产生不良行为影响。
