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[内胚层抗原在犬类器官和组织中的定位]

[Localization of endodermal antigen in the organs and tissues of dogs].

作者信息

Séérdre T P, Isaev V N, Mamiliaeva Z Kh

出版信息

Biull Eksp Biol Med. 1980 Nov;90(11):569-70.

PMID:7004525
Abstract

Spontaneous stomatitis in dogs gives rise to the appearance in ectodermal derivatives of an additional antigen that is not detectable in normal oral mucosa. The immunofluorescence and immunoperoxidase methods were used to study the intracellular localization of entodermal antigen in various part of the alimentary tract. Clear and contrast localization of the test antigen in all parts of the alimentary tract warrants a conclusion that this antigen is a mucus component secreted by alimentary tract glands. No antigen under test was found in oral mucosa portions of entodermal origin except for soft palate. Entodermal antigen was not detected either in small mucus-forming glands.

摘要

犬自发性口炎会导致外胚层衍生物中出现一种在正常口腔黏膜中无法检测到的额外抗原。采用免疫荧光和免疫过氧化物酶方法研究内胚层抗原在消化道各部位的细胞内定位。试验抗原在消化道所有部位的清晰且对比明显的定位表明,该抗原是消化道腺体分泌的一种黏液成分。除软腭外,在内胚层来源的口腔黏膜部分未发现受试抗原。在小型黏液形成腺体中也未检测到内胚层抗原。

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