丹曲林钠混悬液治疗痉挛型脑瘫。
Dantrolene sodium suspension in treatment of spastic cerebral palsy.
作者信息
Joynt R L, Leonard J A
出版信息
Dev Med Child Neurol. 1980 Dec;22(6):755-67. doi: 10.1111/j.1469-8749.1980.tb03742.x.
Abstract
A double-blind study was carried out on 20 children with spasticity secondary to cerebral palsy, in order to compare the effects of dantrolene sodium suspension and a placebo. The drug was found to be physiologically active in reducing the force of muscle contraction, but objective functional improvement, as measured by multiple performance tests, was irregular and probably not significant.
摘要
对20名患有脑瘫继发性痉挛的儿童进行了一项双盲研究，以比较丹曲林钠混悬液和安慰剂的效果。结果发现，该药物在降低肌肉收缩力方面具有生理活性，但通过多项性能测试衡量的客观功能改善并不规律，可能也不显著。
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