Balakrishnan S
Lepr India. 1980 Apr;52(2):245-8.
The DDS/Crestinine ratios obtained by the colorimetric and fluorimetric methods for dapsone were compared in healthy controls, out-patients not claiming to have DDS treatment and inpatients receiving DDS. The ratios by fluorimetric method were considerably lower in the untreated cases compared to the colorimetric method. Fluorimetric assay for dapsone in urine can be more advantageously and reliably used for the preliminary screening of dapsone in urine for drug trials.
在健康对照者、未声称接受氨苯砜治疗的门诊患者以及接受氨苯砜治疗的住院患者中，比较了用比色法和荧光法测定的氨苯砜的DDS/肌酐比值。与比色法相比，荧光法测得的未治疗病例的比值要低得多。尿液中氨苯砜的荧光测定法可更有利且可靠地用于药物试验中尿液氨苯砜的初步筛查。
