Svennevig J L, Bugge-Asperheim B, Birkeland S, Bjørgo S
Acta Chir Scand Suppl. 1980;499:87-92.
Haemodynamic, metabolic and clinical data were recorded in patients suffering from lung contusion following blunt chest trauma. The effects of large doses of methylprednisolone (30 mg per kg b.w.) were studied in 10 patients selected at random, and compared with 10 patients receiving no steroids, but who otherwise were treated in the same way. Serious post-traumatic complications were reduced in the steroid group. The beneficial effect of the steroid treatment seemed to be associated with a significant reduction in pulmonary vascular resistance, which may lead to a better tissue perfusion and a reduction of right heart work.
记录了钝性胸部创伤后肺挫伤患者的血流动力学、代谢和临床数据。对随机选取的10例患者研究了大剂量甲基泼尼松龙（30mg/kg体重）的作用，并与10例未接受类固醇治疗但其他治疗方式相同的患者进行比较。类固醇组创伤后严重并发症减少。类固醇治疗的有益作用似乎与肺血管阻力显著降低有关，这可能导致更好的组织灌注和右心工作量减少。
