Schelbert H R, Phelps M E, Hoffman E, Huang S C, Kuhl D E
Am J Cardiol. 1980 Dec 18;46(7):1269-77. doi: 10.1016/0002-9149(80)90298-2.
Positron emission computed tomography is a new technique of potential value for the noninvasive measurement of myocardial blood flow, mechanical function and, in particular, metabolism. The capability of this new study method is attributable to the technologic innovations of the imaging device and the availability of radioactive tracers that are specific for blood flow and metabolism. The device permits recording of cross-sectional images of the left ventricular myocardium that quantitatively reflect regional tracer tissue concentrations. Use of tracer kinetic models with this new technique permits measurements of regional glucose and fatty acid metabolism of the heart. Positron emission tomography is already an important new tool for investigative studies of cardiac physiology and pathophysiology; its clinical utility remains to be defined.
正电子发射计算机断层扫描是一种具有潜在价值的新技术，可用于无创测量心肌血流、机械功能，尤其是代谢。这种新研究方法的能力归因于成像设备的技术创新以及可获得的针对血流和代谢的放射性示踪剂。该设备能够记录左心室心肌的横断面图像，这些图像可定量反映局部示踪剂组织浓度。将示踪剂动力学模型与这项新技术结合使用，可以测量心脏局部的葡萄糖和脂肪酸代谢。正电子发射断层扫描已经是心脏生理学和病理生理学研究的一项重要新工具；其临床应用价值仍有待确定。
