致敏淋巴细胞定型：试剂制备及HLA - D区抗原的定义

Primed LD typing: reagent preparation and definition of the HLA-D-region antigens.

作者信息

Bach F H, Jarrett-Toh E K, Benike C J, Shih C Y, Valentine E A, Sondel P M, Bach M L

出版信息

Scand J Immunol. 1977;6(5):469-75. doi: 10.1111/j.1365-3083.1977.tb02105.x.

DOI:10.1111/j.1365-3083.1977.tb02105.x

Abstract

Primed LD typing cells were prepared against single HLA haplotypes within families and used to type a random panel of 48 individuals. PLT cells could be grouped on the basis of highly correlated responses with the panel test cells; the 21 different PLT cells could be used to define 6 different PL antigens. One of these, PL 3, was split by the responses of two of the 21 PLT cells which measured an antigen called PL 3.1.

摘要

针对家族内单个HLA单倍型制备致敏的LD分型细胞，并用于对48名个体的随机样本进行分型。PLT细胞可根据与面板测试细胞的高度相关反应进行分组；21种不同的PLT细胞可用于定义6种不同的PL抗原。其中之一，PL 3，被21种PLT细胞中的两种细胞反应所拆分，这两种细胞检测到一种名为PL 3.1的抗原。