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沙漠啮齿动物肥尾心颅跳鼠远端肾单位向集合管过渡区的超微结构组织

Ultrastructural organization of the transition from the distal nephron to the collecting duct in the desert rodent Psammomys obesus.

作者信息

Kaissling B

出版信息

Cell Tissue Res. 1980;212(3):475-95. doi: 10.1007/BF00236512.

DOI:10.1007/BF00236512
PMID:7006826
Abstract

The transition from the nephron to the collecting duct is formed by three tubular segments (convoluted part of the distal tubule, connecting tubule, cortical collecting duct), which in the desert rodent, Psammomys obesus, transform gradually from one segment to the next, due to intermingling of their different cell types. The convoluted part of the distal tubule (DTC) starts abruptly, shortly beyond the macula densa and initially is homogeneously composed of characteristic DTC-cells. Subsequently, the DTC-cells intermingle with intercalated cells. The first appearance of the connecting-tubule cell, which gradually replaces the DTC-cell, is regarded as the beginning of the connecting tubule. The major portion of the connecting tubule is lined by connecting-tubule cells and intercalated cells. The first appearance of the principal cell between them defines the beginning of the cortical collecting duct, which in the medullary ray is lined by principal and intercalated cells only. Each cell type is described in detail and discussed in relation to the assumed function of the tubular segments. Interspecies differences in the cellular composition of the transitional zone from the nephron to the collecting duct are discussed in relation to the different organization of the collecting duct system.

摘要

从肾单位到集合管的过渡由三个管状节段组成(远曲小管的卷曲部分、连接小管、皮质集合管),在沙漠啮齿动物欧氏肥尾沙鼠中,由于不同细胞类型的相互混合,这些节段会逐渐从一个节段转变为下一个节段。远曲小管的卷曲部分(DTC)在致密斑稍远处突然开始,最初由特征性的DTC细胞均匀组成。随后,DTC细胞与闰细胞相互混合。连接小管细胞的首次出现逐渐取代了DTC细胞,这被视为连接小管的开始。连接小管的主要部分由连接小管细胞和闰细胞内衬。它们之间主细胞的首次出现定义了皮质集合管的开始,在髓放线中,皮质集合管仅由主细胞和闰细胞内衬。详细描述了每种细胞类型,并结合管状节段的假定功能进行了讨论。还讨论了从肾单位到集合管过渡区细胞组成的种间差异与集合管系统不同组织的关系。

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引用本文的文献

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Ultrastructure of the kidney of a South American caecilian, Typhlonectes compressicaudus (Amphibia, Gymnophiona). II. Distal tubule, connecting tubule, collecting duct and Wolffian duct.南美蚓螈Typhlonectes compressicaudus(两栖纲,蚓螈目)肾脏的超微结构。II. 远端小管、连接小管、集合管和中肾管
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Distribution of 5'-nucleotidase in the renal interstitium of the rat.5'-核苷酸酶在大鼠肾间质中的分布
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Morphologic alterations in the rat medullary collecting duct following potassium depletion.钾缺乏后大鼠髓质集合管的形态学改变。
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