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Detection by three cellular immunological techniques of the antigenic determinants of the Ly-Li system, expressed on human B lymphocytes.

作者信息

Sasportes M, Mawas C, Crosier P, Charmot D, Legrand L, Dausset J

出版信息

Scand J Immunol. 1977;6(5):507-10. doi: 10.1111/j.1365-3083.1977.tb02112.x.

DOI:10.1111/j.1365-3083.1977.tb02112.x
PMID:70070
Abstract

A clear correlation was observed between the presence of an Ia-like antigenic B-cell system Ly-Li, detected serologically, and three cellular immunological techniques: [1] mixed lymphocyte reaction (MLR) inhibition by an anti-Li antiserum; [2] level of restimulation of anti-Ly-Li in-vitro-primed lymphocytes; and [3] detection of HLA-D alleles by homozygous typing cells. These results suggested that the allelic products detected serologically may be identical to those detected by the first two techniques, namely MLR inhibition and in-vitro-primed lymphocyte typing, and, possibly, HLA-D typing using homozygous typing cells, although the correlation was repeatedly found to be less clear for the last technique.

摘要

相似文献

1
Detection by three cellular immunological techniques of the antigenic determinants of the Ly-Li system, expressed on human B lymphocytes.
Scand J Immunol. 1977;6(5):507-10. doi: 10.1111/j.1365-3083.1977.tb02112.x.
2
[Determination by three technics of cellular immunology of the antigenic determinants of the Ly-Li system expressed on human B lymphocytes].
C R Acad Hebd Seances Acad Sci D. 1976 Sep 27;283(6):663-6.
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[The Ly-Li system, a new locus of the HLA complex].[Ly-Li系统,HLA复合体的一个新位点]
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Transplant Proc. 1978 Mar;10(1):57-62.
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B-cell alloantigens in two recombinant families: prediction of a B/D recombination using B-cell-specific alloantisera.两个重组家族中的B细胞同种异体抗原:利用B细胞特异性同种异体抗血清预测B/D重组
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The comparison between normal and Epstein-Barr virus-transformed homozygous typing cells and their use for MLC, PLT and serological detection of human Ia-type alloantigens.正常与爱泼斯坦-巴尔病毒转化的纯合分型细胞之间的比较及其在人类Ia型同种异体抗原的混合淋巴细胞培养、血小板淋巴细胞试验和血清学检测中的应用。
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Specificity of human lymphocytes primed against allogeneic cells in vitro. 1. Optimalization of culture conditions for detection of HLA--D specificity.体外针对同种异体细胞致敏的人淋巴细胞的特异性。1. 检测HLA-D特异性的培养条件优化。
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Complexity of the HLA-D region studied by primed-lymphocyte test.通过致敏淋巴细胞试验研究的HLA - D区域的复杂性。
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Predictive value of HLA class II PCR typing for the outcome of mixed lymphocyte reaction.人类白细胞抗原II类PCR分型对混合淋巴细胞反应结果的预测价值
Folia Biol (Praha). 1998;44(4):137-41.

引用本文的文献

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Heterogeneity of HLA defined in PLT: a cellular assay detects differences not seen using HLA-DRw serology.血小板 HLA 定义的异质性:细胞分析检测到 HLA-DRw 血清学未见的差异。
Immunogenetics. 1980;10(6):513-20. doi: 10.1007/BF01572586.