Don G J, Shearman D J, Hecker R
Med J Aust. 1980 Nov 15;2(10):567-8. doi: 10.5694/j.1326-5377.1980.tb100771.x.
Twenty-three patients with chronic duodenal ulcer were allocated randomly to receive either trimipramine 25 mg or placebo, as a single night-time dose, for six weeks. Ulcer healing was determined by endoscopy. The ulcer healed in two of 10 patients receiving trimipramine and in seven of 13 patients receiving placebo. Trimipramine in this dosage does not assist ulcer healing.
23名患有慢性十二指肠溃疡的患者被随机分配，每晚单次服用25毫克三甲丙咪嗪或安慰剂，为期六周。通过内窥镜检查确定溃疡愈合情况。接受三甲丙咪嗪治疗的10名患者中有2名溃疡愈合，接受安慰剂治疗的13名患者中有7名溃疡愈合。这种剂量的三甲丙咪嗪无助于溃疡愈合。
