硝苯地平治疗心绞痛和慢性气道阻塞的疗效。
Efficacy of nifedipine in the treatment of angina pectoris and chronic airways obstruction.
作者信息
Jaiprakash S S, Sahay J N, Chatterjee S S, MacDonald G
出版信息
Postgrad Med J. 1980 Sep;56(659):624-8. doi: 10.1136/pgmj.56.659.624.
Abstract
Twenty patients suffering from angina pectoris with co-existing fixed or labile airways obstruction, were administered fortnightly treatment periods of nifedipine or matching placebo over an 8-week period. Maintenance treatment for their airways obstruction continued throughout this period. Nifedipine was found to be an effective drug in controlling their angina, and did not have an adverse effect on the airways obstruction. Both systolic and diastolic BP was reduced over a 90-min period after administration of a single dose of nifedipine.
摘要
20名患有心绞痛且伴有固定性或易变性气道阻塞的患者，在8周内每两周接受一次硝苯地平或匹配安慰剂的治疗。在此期间，他们的气道阻塞维持治疗持续进行。结果发现硝苯地平是控制其心绞痛的有效药物，且对气道阻塞没有不良影响。单次服用硝苯地平后90分钟内，收缩压和舒张压均有所降低。
相似文献
1
Efficacy of nifedipine in the treatment of angina pectoris and chronic airways obstruction.
Postgrad Med J. 1980 Sep;56(659):624-8. doi: 10.1136/pgmj.56.659.624.
2
Efficacy of nifedipine therapy in patients with refractory angina pectoris: significance of the presence of coronary vasospasm.
Am Heart J. 1983 Oct;106(4 Pt 1):644-52. doi: 10.1016/0002-8703(83)90081-9.
3
4
Comparison of atenolol and oxprenolol in patients with angina or hypertension and co-existent chronic airways obstruction.
Br J Clin Pharmacol. 1978 Feb;5(2):101-6. doi: 10.1111/j.1365-2125.1978.tb01608.x.
5
6
[Nifedipine (adalate) in the treatment of angina pectoris].
Vutr Boles. 1978;17(1):40-6.
7
[Nifedipine and verapamil in unstable angina. Evaluation by the Holter method].
Rev Esp Cardiol. 1982;35(5 Suppl 2):II61-4.
8
Alternatives to beta-blockade in therapy of hypertension with angina pectoris: role of nifedipine or of labetalol.
Br J Clin Pharmacol. 1982 Jun;13(1 Suppl):115S-122S. doi: 10.1111/j.1365-2125.1982.tb01899.x.
9
Nifedipine in medically refractory angina pectoris.
Med J Aust. 1981 Sep 19;2(6):288-9. doi: 10.5694/j.1326-5377.1981.tb128320.x.
10
A retrospective evaluation of nifedipine therapy in Prinzmetal's angina.
J Int Med Res. 1979;7(5):360-9. doi: 10.1177/030006057900700505.
引用本文的文献
1
A calcium antagonist, nifedipine, modifies exercise-induced asthma.
Thorax. 1981 Oct;36(10):726-30. doi: 10.1136/thx.36.10.726.
2
Effect of nifedipine on bronchomotor tone and histamine reactivity in asthma.
Br Med J (Clin Res Ed). 1981 Aug 1;283(6287):348. doi: 10.1136/bmj.283.6287.348.
3
Calcium-channel blockers and asthma.
Thorax. 1983 Jul;38(7):481-5. doi: 10.1136/thx.38.7.481.
4
Calcium channel blockers and asthma.
Lung. 1986;164(1):1-16. doi: 10.1007/BF02713625.
5
Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders.
Drugs. 1985 Sep;30(3):182-274. doi: 10.2165/00003495-198530030-00002.
本文引用的文献
1
EFFECT OF A BETA-ADRENERGIC-BLOCKING AGENT, PROPRANOLOL, ON ASTHMATICS.
Lancet. 1964 Nov 21;2(7369):1101-2. doi: 10.1016/s0140-6736(64)92617-0.
2
Comparison of effects of metoprolol and propranolol on asthmatic airway obstruction.
Br Med J. 1976 Feb 28;1(6008):504. doi: 10.1136/bmj.1.6008.504.
3
Effects of muliple doses of metoprolol and propranolol on ventilatory function in patients with chronic obstructive lung disease.
Scand J Respir Dis. 1976;57(4):190-6.
4
Acute and chronic effects of nifedipine in arterial hypertension.
Eur J Clin Pharmacol. 1978 Dec 18;14(6):375-81. doi: 10.1007/BF00716377.
5
Relaxing effects of Nifedipine on the nonpregnant human uterus in vitro and in vivo.
Obstet Gynecol. 1978 Oct;52(4):436-41.
6
Effects of nifedipine on the smooth muscle of the human urinary tract in vitro and in vivo.
Acta Pharmacol Toxicol (Copenh). 1978 Aug;43(2):111-8. doi: 10.1111/j.1600-0773.1978.tb02244.x.
7
[Clinical and experimental studies on the efficiency of nifedipine on smooth muscle strips of the esophagus (author's transl)].
Z Gastroenterol. 1977 Nov;15(11):691-8.
8
Inhibition of prostaglandin-induced uterine activity by nifedipine.
Br J Obstet Gynaecol. 1979 Mar;86(3):175-9. doi: 10.1111/j.1471-0528.1979.tb10590.x.
9
Antianginal efficiency of nifedipine with and without a beta-blocker, studied with exercise test. A double-blind, randomized subacute study.
Clin Cardiol. 1979 Jun;2(3):203-11. doi: 10.1002/clc.4960020306.
10
A double-blind controlled trial of the anti-anginal efficacy of nifedipine compared with propranolol.
Br J Clin Pract. 1979 Feb;33(2):49-51.
Zotero 插件