硝苯地平治疗心绞痛和慢性气道阻塞的疗效。
Efficacy of nifedipine in the treatment of angina pectoris and chronic airways obstruction.
作者信息
Jaiprakash S S, Sahay J N, Chatterjee S S, MacDonald G
出版信息
Postgrad Med J. 1980 Sep;56(659):624-8. doi: 10.1136/pgmj.56.659.624.
Abstract
Twenty patients suffering from angina pectoris with co-existing fixed or labile airways obstruction, were administered fortnightly treatment periods of nifedipine or matching placebo over an 8-week period. Maintenance treatment for their airways obstruction continued throughout this period. Nifedipine was found to be an effective drug in controlling their angina, and did not have an adverse effect on the airways obstruction. Both systolic and diastolic BP was reduced over a 90-min period after administration of a single dose of nifedipine.
摘要
20名患有心绞痛且伴有固定性或易变性气道阻塞的患者，在8周内每两周接受一次硝苯地平或匹配安慰剂的治疗。在此期间，他们的气道阻塞维持治疗持续进行。结果发现硝苯地平是控制其心绞痛的有效药物，且对气道阻塞没有不良影响。单次服用硝苯地平后90分钟内，收缩压和舒张压均有所降低。
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