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Postgrad Med J. 1980 Sep;56(659):624-8. doi: 10.1136/pgmj.56.659.624.
2
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[Varying response to nifedipine during treatment of stable exertional angina pectoris: results of a double-blind, randomized, cross-over, placebo-controlled study (author's transl)].[硝苯地平治疗稳定型劳力性心绞痛期间的不同反应：一项双盲、随机、交叉、安慰剂对照研究的结果（作者译）]
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Calcium channel blockers and asthma.钙通道阻滞剂与哮喘
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Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders.硝苯地平。对其在缺血性心脏病、高血压及相关心血管疾病中的药效学、药代动力学特性及治疗效果的综述。
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1
EFFECT OF A BETA-ADRENERGIC-BLOCKING AGENT, PROPRANOLOL, ON ASTHMATICS.β-肾上腺素能阻滞剂普萘洛尔对哮喘患者的影响。
Lancet. 1964 Nov 21;2(7369):1101-2. doi: 10.1016/s0140-6736(64)92617-0.
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Comparison of effects of metoprolol and propranolol on asthmatic airway obstruction.美托洛尔与普萘洛尔对哮喘气道阻塞影响的比较
Br Med J. 1976 Feb 28;1(6008):504. doi: 10.1136/bmj.1.6008.504.
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Effects of muliple doses of metoprolol and propranolol on ventilatory function in patients with chronic obstructive lung disease.
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Acute and chronic effects of nifedipine in arterial hypertension.硝苯地平在动脉高血压中的急性和慢性作用。
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Relaxing effects of Nifedipine on the nonpregnant human uterus in vitro and in vivo.
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Effects of nifedipine on the smooth muscle of the human urinary tract in vitro and in vivo.硝苯地平对人泌尿道平滑肌的体内外作用
Acta Pharmacol Toxicol (Copenh). 1978 Aug;43(2):111-8. doi: 10.1111/j.1600-0773.1978.tb02244.x.
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[Clinical and experimental studies on the efficiency of nifedipine on smooth muscle strips of the esophagus (author's transl)].
Z Gastroenterol. 1977 Nov;15(11):691-8.
8
Inhibition of prostaglandin-induced uterine activity by nifedipine.硝苯地平对前列腺素诱导的子宫活动的抑制作用。
Br J Obstet Gynaecol. 1979 Mar;86(3):175-9. doi: 10.1111/j.1471-0528.1979.tb10590.x.
9
Antianginal efficiency of nifedipine with and without a beta-blocker, studied with exercise test. A double-blind, randomized subacute study.硝苯地平联合或不联合β受体阻滞剂的抗心绞痛疗效，通过运动试验进行研究。一项双盲、随机亚急性研究。
Clin Cardiol. 1979 Jun;2(3):203-11. doi: 10.1002/clc.4960020306.
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A double-blind controlled trial of the anti-anginal efficacy of nifedipine compared with propranolol.
Br J Clin Pract. 1979 Feb;33(2):49-51.

硝苯地平治疗心绞痛和慢性气道阻塞的疗效。

Efficacy of nifedipine in the treatment of angina pectoris and chronic airways obstruction.

作者信息

Jaiprakash S S, Sahay J N, Chatterjee S S, MacDonald G

出版信息

Postgrad Med J. 1980 Sep;56(659):624-8. doi: 10.1136/pgmj.56.659.624.

DOI:10.1136/pgmj.56.659.624
PMID:7008048
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2425946/
Abstract

Twenty patients suffering from angina pectoris with co-existing fixed or labile airways obstruction, were administered fortnightly treatment periods of nifedipine or matching placebo over an 8-week period. Maintenance treatment for their airways obstruction continued throughout this period. Nifedipine was found to be an effective drug in controlling their angina, and did not have an adverse effect on the airways obstruction. Both systolic and diastolic BP was reduced over a 90-min period after administration of a single dose of nifedipine.

摘要

20名患有心绞痛且伴有固定性或易变性气道阻塞的患者，在8周内每两周接受一次硝苯地平或匹配安慰剂的治疗。在此期间，他们的气道阻塞维持治疗持续进行。结果发现硝苯地平是控制其心绞痛的有效药物，且对气道阻塞没有不良影响。单次服用硝苯地平后90分钟内，收缩压和舒张压均有所降低。