利巴韦林治疗单纯疱疹病毒生殖器感染的临床疗效。
Clinical efficacy of ribavirin in the treatment of genital herpes simplex virus infection.
作者信息
Bierman S M, Kirkpatrick W, Fernandez H
出版信息
Chemotherapy. 1981;27(2):139-45. doi: 10.1159/000237969.
PMID:7009087
Abstract
48 patients participated in a double-blind placebo-controlled study conducted to evaluate the efficacy of ribavirin in the treatment of herpes simplex virus genital infection. Study design did not allow a conclusion regarding usefulness of the drug in preventing recurrences. Ribavirin treatment (800 mg/day p.o) for 10 days reduced disease severity and promoted recovery as compared with placebo treatment.
摘要
48名患者参与了一项双盲安慰剂对照研究，该研究旨在评估利巴韦林治疗单纯疱疹病毒生殖器感染的疗效。研究设计不允许得出关于该药物在预防复发方面有用性的结论。与安慰剂治疗相比，利巴韦林治疗（口服800毫克/天）持续10天可减轻疾病严重程度并促进恢复。
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