大肠杆菌β-内酰胺酶衰减子介导生长速率依赖性调控。
The E. coli beta-lactamase attenuator mediates growth rate-dependent regulation.
作者信息
Jaurin B, Grundström T, Edlund T, Normark S
出版信息
Nature. 1981 Mar 19;290(5803):221-5. doi: 10.1038/290221a0.
DOI:10.1038/290221a0
PMID:7010184
Abstract
We have identified a new control or attenuator region in the chromosomal beta-lactamase operon of Escherichia coli. A single base alteration within its attenuator led to a loss in the cell's ability to coordinate its content of beta-lactamase with growth rate. We suggest a mechanism through which this mode of regulation operates.
摘要
我们在大肠杆菌的染色体β-内酰胺酶操纵子中鉴定出一个新的调控或衰减区域。其衰减子内的单个碱基改变导致细胞协调β-内酰胺酶含量与生长速率的能力丧失。我们提出了一种这种调控模式发挥作用的机制。
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