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人类和高等动物体内的多胺代谢产物与共轭物:文献综述

Polyamine metabolites and conjugates in man and higher animals: a review of the literature.

作者信息

Aigner-Held R, Daves G D

出版信息

Physiol Chem Phys. 1980;12(5):389-400.

PMID:7010391
Abstract

The current state of knowledge of the metabolic fate of the di- and polyamines putrescine, spermidine, and spermine is reviewed. Acetylated, oxidized, and protein-bound polyamines are found to be widely distributed in man and animals. The importance of understanding the roles of these compounds in health and disease is now recognized and is currently the subject of active research.

摘要

本文综述了二胺和多胺(腐胺、亚精胺和精胺)代谢命运的当前知识状态。发现乙酰化、氧化和与蛋白质结合的多胺广泛分布于人和动物体内。现在人们认识到了解这些化合物在健康和疾病中的作用的重要性,并且它们目前是积极研究的主题。

相似文献

1
Polyamine metabolites and conjugates in man and higher animals: a review of the literature.人类和高等动物体内的多胺代谢产物与共轭物:文献综述
Physiol Chem Phys. 1980;12(5):389-400.
2
Conjugation of radiolabeled polyamines in the rat.大鼠体内放射性标记多胺的结合
Cancer Res. 1977 Jan;37(1):47-51.
3
Simultaneous determination of endogenous and orally administered (15)N-labeled polyamines in rat organs.同时测定大鼠器官中内源性和口服给予的(15)N标记多胺。
Anal Biochem. 2002 Feb 15;301(2):255-60. doi: 10.1006/abio.2001.5510.
4
Acetylation of polyamines in mouse brain: subcellular and regional distribution.小鼠脑中多胺的乙酰化:亚细胞和区域分布
J Neurosci Res. 1983;9(2):193-201. doi: 10.1002/jnr.490090211.
5
Differential conjugation of polyamines to calf nuclear and nucleolar proteins.多胺与小牛细胞核及核仁蛋白的差异共轭作用。
J Cell Physiol. 1981 Dec;109(3):447-52. doi: 10.1002/jcp.1041090310.
6
[Synthesis of polyamine hydrochlorides and their oxidative deamination by diamine oxidase from rapidly growing tissues].[多胺盐酸盐的合成及其在快速生长组织中被二胺氧化酶进行的氧化脱氨反应]
Vopr Med Khim. 1980 May-Jun;26(3):322-5.
7
Formation of acetylpolyamines and putrescine from spermidine by normal and transformed chick embryo fibroblasts.正常和转化的鸡胚成纤维细胞将亚精胺转化为乙酰多胺和腐胺的过程。
Cancer Res. 1981 Mar;41(3):1205-8.
8
Uptake and disposition of putrescine, spermidine, and spermine by rabbit lungs.兔肺对腐胺、亚精胺和精胺的摄取与分布
Drug Metab Dispos. 1987 Mar-Apr;15(2):189-94.
9
[Oxidation of putrescine, spermidine and spermine by diamino-oxidase from mouse liver].[小鼠肝脏二胺氧化酶对腐胺、亚精胺和精胺的氧化作用]
Biokhimiia. 1977 Jun;42(6):1010-3.
10
Changes in endogenous polyamine levels are associated with differentiation in Dictyostelium discoideum.内源性多胺水平的变化与盘基网柄菌的分化有关。
Cell Biol Int. 1998;22(7-8):575-80. doi: 10.1006/cbir.1998.0297.

引用本文的文献

1
Polyamines are inhibitors of gastric acid secretion.多胺是胃酸分泌的抑制剂。
Proc Natl Acad Sci U S A. 1982 Mar;79(5):1448-52. doi: 10.1073/pnas.79.5.1448.
2
Oral administration of spermine inhibits gastric acid secretion in rats.口服精胺可抑制大鼠胃酸分泌。
Dig Dis Sci. 1983 Jun;28(6):513-7. doi: 10.1007/BF01308153.
3
Oxidized polyamines and the growth of human vascular endothelial cells. Prevention of cytotoxic effects by selective acetylation.氧化多胺与人类血管内皮细胞的生长。通过选择性乙酰化预防细胞毒性作用。
Biochem J. 1987 Mar 1;242(2):347-52. doi: 10.1042/bj2420347.
4
The effect of amino acids, monoamines and polyamines on pyruvate dehydrogenase activity in mitochondria from rat adipocytes.氨基酸、单胺和多胺对大鼠脂肪细胞线粒体中丙酮酸脱氢酶活性的影响。
Mol Cell Biochem. 1990 Mar 27;93(2):195-206. doi: 10.1007/BF00226192.