人成熟子宫颈中前列环素合成活性增加。

Increased prostacyclin synthesizing activity in human ripening uterine cervix.

作者信息

Tanaka M, Morita I, Hirakawa S, Murota S

出版信息

Prostaglandins. 1981 Jan;21(1):83-6. doi: 10.1016/0090-6980(81)90198-2.

Abstract

Homogenate of human uterine cervix at delivery were incubated with radioactive arachidonic acid. A major metabolite (conversion rate, approx. 20%) was identified with 6-ketoprostaglandin F1 alpha, a metabolite of prostacyclin. The 6-ketoprostaglandin F1 alpha production in the ripening cervix was more than 6 times per wet weight and 37 times per DNA as much as that in the non-pregnant cervix.

摘要

分娩时的人子宫颈匀浆与放射性花生四烯酸一起孵育。一种主要代谢产物（转化率约为20%）被鉴定为6-酮前列腺素F1α，即前列环素的一种代谢产物。成熟子宫颈中6-酮前列腺素F1α的产生量按湿重计算是未孕子宫颈的6倍多，按DNA计算是未孕子宫颈的37倍。