Tschochner H J, Göhler H, Frühauf G
Z Urol Nephrol. 1980 Sep;73(9):681-6.
A bacteriuria tablet test based on methyl-blue reduction was examined for its reliability as screening method for the recognition of infections of the urinary tract. 860 urine specimens of male and female patients were investigated which had been got before the beginning of an antibiotic therapy. Apart from simple handling and little expenses the tablet test distinguishes itself by a sensitivity of 99.3% in infected urines with numbers of germs = 10(5) K/ml urine and 96% in the urine specimens infected by pathogenic germs abd a number of germs of 5 X 10(4)--10(5) K/ml urine, respectively. Contamination germs are in most cases suppressed by the tablet test. The specificity in our investigation material is about 97.2%. In a positive result of the reaction it is possible to send the specimens for the differentiation of germs and for the antibiogram directly to the nearest bacteriological laboratory. This test gives the possibility systematically to control endangered groups of persons in large quantity and to begin an aimed therapy in significant bacteriuria without any greater delay according to the findings of the antibiogram.
对一种基于亚甲基蓝还原的尿菌片试验作为筛查尿路感染的方法进行了可靠性研究。对860例男女患者服用抗生素治疗前采集的尿液样本进行了检测。尿菌片试验除操作简单和成本较低外，对于每毫升尿液中细菌数≥10⁵CFU/ml的感染尿液，其敏感性为99.3%；对于每毫升尿液中细菌数为5×10⁴-10⁵CFU/ml且被病原菌感染的尿液样本，敏感性分别为96%。大多数情况下，污染菌可被尿菌片试验抑制。在我们的研究材料中，特异性约为97.2%。如果反应结果为阳性，可将样本直接送至最近的细菌学实验室进行细菌鉴定和药敏试验。该试验能够系统地对大量高危人群进行检测，并根据药敏试验结果，在显著菌尿时及时开始有针对性的治疗，且不会有太大延误。
