Hedström S A, Lidgren L, Törholm C, Onnerfält R
Acta Orthop Scand. 1980 Dec;51(6):863-9. doi: 10.3109/17453678008990886.
Forty-eight cases of osteomyelitis or bacterial arthritis operated on with eradication of infections lesions were randomly treated either by insertion of suction-irrigation drainage or by implantation of gentamicin beads. The average follow-up time was 2 years. There was no difference in the recurrence rate between the two groups. The gentamicin treated patients were however more easily cared for as the suction-irrigation drainage required constant attention. Local temporary treatment with gentamicin beads should be used in cases of deep gram-negative muscle and skeletal infections where it would otherwise be necessary to give toxic antibiotics.
48例接受感染病灶清除手术的骨髓炎或细菌性关节炎患者被随机分为两组，分别接受吸引冲洗引流或庆大霉素珠植入治疗。平均随访时间为2年。两组的复发率没有差异。然而，庆大霉素治疗组的患者护理起来更容易，因为吸引冲洗引流需要持续关注。对于深部革兰氏阴性肌肉和骨骼感染病例，若不使用庆大霉素珠进行局部临时治疗，则有必要使用毒性较大的抗生素。
