Carson E R, Cobelli C, Finkelstein L
Am J Physiol. 1981 Mar;240(3):R120-9. doi: 10.1152/ajpregu.1981.240.3.R120.
Introductory principles of physiological systems analysis by computer simulation or computation are introduced. The problems of model formulation, identification, and validation are examined. Selected guidelines for successful modeling are suggested, and examples of such applications in the field of endocrinology and metabolism are given.
介绍了通过计算机模拟或计算进行生理系统分析的入门原理。研究了模型制定、识别和验证的问题。提出了成功建模的选定指南，并给出了在内分泌学和代谢领域的此类应用示例。
