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Validation of mathematical models of complex endocrine-metabolic systems. A case study on a model of glucose regulation.

作者信息

Cobelli C, Mari A

出版信息

Med Biol Eng Comput. 1983 Jul;21(4):390-9. doi: 10.1007/BF02442625.

DOI:10.1007/BF02442625
PMID:6350741
Abstract
摘要

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Validation of mathematical models of complex endocrine-metabolic systems. A case study on a model of glucose regulation.复杂内分泌代谢系统数学模型的验证。以葡萄糖调节模型为例的研究。
Med Biol Eng Comput. 1983 Jul;21(4):390-9. doi: 10.1007/BF02442625.
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Mathematical model for glucose regulation in the whole-body system.全身系统葡萄糖调节的数学模型。
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A composite computational model of liver glucose homeostasis. II. Exploring system behaviour.肝脏葡萄糖稳态的综合计算模型。II. 探索系统行为。
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Diabetes. 1978 Oct;27(10):1027-42. doi: 10.2337/diab.27.10.1027.

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本文引用的文献

1
The role of fractional glucose extraction in the regulation of splanchnic glucose metabolism in normal and diabetic man.正常人和糖尿病患者中葡萄糖摄取分数在调节内脏葡萄糖代谢中的作用。
Metabolism. 1980 Jan;29(1):28-35. doi: 10.1016/0026-0495(80)90094-3.
2
Modeling and identification of metabolic systems.代谢系统的建模与识别
Am J Physiol. 1981 Mar;240(3):R120-9. doi: 10.1152/ajpregu.1981.240.3.R120.
3
Insulin, glucagon, and amino acids during glycemic control by the artificial pancreas in diabetic man.糖尿病患者使用人工胰腺进行血糖控制期间的胰岛素、胰高血糖素和氨基酸
一种基于胰岛素储备估计的改进型PID算法用于1型糖尿病的血糖控制
Comput Math Methods Med. 2015;2015:281589. doi: 10.1155/2015/281589. Epub 2015 Oct 5.
4
A comprehensive compartmental model of blood glucose regulation for healthy and type 2 diabetic subjects.一种针对健康受试者和2型糖尿病患者的血糖调节综合房室模型。
Med Biol Eng Comput. 2016 Sep;54(9):1383-98. doi: 10.1007/s11517-015-1406-4. Epub 2015 Oct 22.
5
A composite model of glucagon-glucose dynamics for in silico testing of bihormonal glucose controllers.用于双激素血糖控制器计算机模拟测试的胰高血糖素-葡萄糖动力学复合模型。
J Diabetes Sci Technol. 2013 Jul 1;7(4):941-51. doi: 10.1177/193229681300700416.
6
Artificial pancreas: past, present, future.人工胰腺：过去、现在与未来。
Diabetes. 2011 Nov;60(11):2672-82. doi: 10.2337/db11-0654.
7
Pharmacokinetic-Pharmacodynamic Modeling of Metformin for the Treatment of Type II Diabetes Mellitus.二甲双胍治疗2型糖尿病的药代动力学-药效学模型
Open Biomed Eng J. 2011;5:1-7. doi: 10.2174/1874120701105010001. Epub 2011 Jan 19.
8
A hierarchical whole-body modeling approach elucidates the link between in Vitro insulin signaling and in Vivo glucose homeostasis.一种分层式全身建模方法阐明了体外胰岛素信号与体内葡萄糖动态平衡之间的联系。
J Biol Chem. 2011 Jul 22;286(29):26028-41. doi: 10.1074/jbc.M110.188987. Epub 2011 May 13.
9
Diabetes: Models, Signals, and Control.糖尿病：模型、信号与控制
IEEE Rev Biomed Eng. 2009 Jan 1;2:54-96. doi: 10.1109/RBME.2009.2036073.
10
Glucose estimation and prediction through meal responses using ambulatory subject data for advisory mode model predictive control.利用动态受试者数据通过进餐反应进行葡萄糖估计和预测，用于咨询模式模型预测控制。
J Diabetes Sci Technol. 2007 Nov;1(6):825-33. doi: 10.1177/193229680700100605.
Metabolism. 1980 Apr;29(4):321-32. doi: 10.1016/0026-0495(80)90005-0.
4
Minimal modeling, partition analysis, and the estimation of insulin sensitivity.最小模型法、分区分析与胰岛素敏感性估计
Fed Proc. 1980 Jan;39(1):110-5.
5
Evaluation of portal/peripheral route and of algorithms for insulin delivery in the closed-loop control of glucose in diabetes--a modeling study.糖尿病血糖闭环控制中胰岛素输注的门静脉/外周途径及算法评估——一项建模研究
IEEE Trans Biomed Eng. 1983 Feb;30(2):93-103. doi: 10.1109/tbme.1983.325203.
6
A model of the kinetics of insulin in man.人体胰岛素动力学模型。
J Clin Invest. 1974 May;53(5):1481-92. doi: 10.1172/JCI107697.
7
The glucose-alanine cycle.葡萄糖-丙氨酸循环
Metabolism. 1973 Feb;22(2):179-207. doi: 10.1016/0026-0495(73)90269-2.
8
Influence of oral glucose ingestion on splanchnic glucose and gluconeogenic substrate metabolism in man.口服葡萄糖对人体内脏葡萄糖及糖异生底物代谢的影响。
Diabetes. 1975 May;24(5):468-75. doi: 10.2337/diab.24.5.468.
9
Reproducibility and comparative analysis of repeated intravenous and oral glucose tolerance tests.重复静脉和口服葡萄糖耐量试验的可重复性及对比分析
Diabetes. 1978 Jul;27(7):715-25. doi: 10.2337/diab.27.7.715.
10
Initial splanchnic extraction of ingested glucose in normal man.正常人体内摄入葡萄糖的初始内脏摄取情况。
Metabolism. 1978 Jun;27(6):657-69. doi: 10.1016/0026-0495(78)90003-3.