Hinsenkamp M, Burny F, Bourgois R, Donkerwolcke M
Aviat Space Environ Med. 1981 Feb;52(2):95-103.
An extensive review of the literature of the aetiology of bone demineralization in weightlessness underline the prevalent effect of mechanical stimulations on bone structure and metabolism. The accurate determination of the mechanical environment of bone can be realized using strain gauges. The results of more than 10 years of clinical application of bone strain measurements demonstrate the interest of this technic. We designed an implantable bone strain transducer composed of a strain gauge embedded in epoxy resin and surrounded by a porous shell. The fixation of the transducer is by bone ingrowth. Results on animals and an acute experimentation on man are presented. The objective of our study in space is to compare the mechanical response of bones of an animal or of a human submitted to normal 1-G gravity and to weightlessness. The average amount of bone strains and their variations during specific movements can be compared.
对失重状态下骨脱矿病因学文献的广泛综述强调了机械刺激对骨骼结构和代谢的普遍影响。使用应变片可以准确测定骨骼的力学环境。超过10年的骨应变测量临床应用结果证明了这项技术的价值。我们设计了一种可植入式骨应变传感器，它由嵌入环氧树脂并被多孔外壳包围的应变片组成。传感器通过骨长入实现固定。文中给出了动物实验结果和人体急性实验结果。我们在太空进行研究的目的是比较处于正常1-G重力和失重状态下的动物或人体骨骼的力学反应。可以比较特定运动过程中骨应变的平均量及其变化情况。
