Howe G R, Sherman G J, Semenciw R M, Miller A B
Can Med Assoc J. 1981 Feb 15;124(4):399-403.
A controlled randomized trial of breast cancer screening has been initiated in Canada. This paper presents an analysis of the possible benefit from screening relative to the possible radiation risk from mammography for those women who will be screened in the trial. It shows that with modern low-dose mammography, even when a conservative estimate of possible reduction in mortality due to early detection is applied to the data, the estimated benefit substantially exceeds any possible hazard.
加拿大已启动一项乳腺癌筛查的对照随机试验。本文分析了该试验中接受筛查的女性,相对于乳腺钼靶检查可能带来的辐射风险,筛查可能带来的益处。结果表明,对于现代低剂量乳腺钼靶检查,即便将早期发现可能降低的死亡率的保守估计应用于数据,估计的益处仍大大超过任何可能的危害。