Kraff M C, Sanders D R, Lieberman H L
J Am Intraocul Implant Soc. 1978 Jul;4(3):107-9. doi: 10.1016/s0146-2776(78)80118-9.
We analyzed the results of a retrospective specular microscopic study of 80 cases with unilateral medallion suture implants and contralateral unoperated eyes. In all cases a clinical estimation of operative endothelial trauma (ET), graded from 0 to 3+, was made at the time of surgery. The mean decrease in endothelial cell density (compared to the unoperated eye) for those 33 patients with ET 0 was 19%. There was a direct correlation between ET and decrease in endothelial cell density up to a mean of 59% for those 18 patients graded ET 2.5 to 3.0. The role of sample bias and small case sampling is significant in explaining the large discrepancy in endothelial cell loss after intraocular lens implantation reported in the literature.
我们分析了一项回顾性镜面显微镜研究的结果，该研究涉及80例单侧奖章缝线植入患者及对侧未手术眼。在所有病例中，手术时对手术引起的内皮损伤（ET）进行了临床评估，分级为0至3+。33例ET为0的患者，其内皮细胞密度平均下降（与未手术眼相比）为19%。对于18例ET分级为2.5至3.0的患者，ET与内皮细胞密度下降之间存在直接相关性，平均下降达59%。样本偏差和小样本抽样在解释文献中报道的人工晶状体植入后内皮细胞损失的巨大差异方面具有重要作用。
