Mehlman M A, Schreiner C A, Mackerer C R
J Environ Pathol Toxicol. 1980 Nov;4(5-6):123-31.
This article summarizes the results of experimental studies on teratogenesis associated with exposure to benzene by oral, parenteral or inhalation routes. Administration of benzene to pregnant experimental animals did not produce marked developmental effects in the fetus at concentrations which did not cause concomitant maternal toxicity. Thus, at maternally nontoxic levels, benzene does not constitute a teratogenic hazard.
本文总结了经口、胃肠外或吸入途径接触苯所致致畸作用的实验研究结果。给怀孕的实验动物施用苯,在未引起母体毒性的浓度下,未对胎儿产生明显的发育影响。因此,在母体无毒的水平下,苯不构成致畸危害。