Schotten A, Esser K J, Habedank M
Z Geburtshilfe Perinatol. 1980 Dec;184(6):449-52.
Amniocentesis was prompted by an hydramnion which existed before the 30th week of pregnancy. Examination of amniotic fluid revealed trisomy 18 with increased alpha-fetoprotein values. Interruption of pregnancy was considered but refused by the patient. This enabled control fetal development during the subsequent weeks. After the patient has given birth to a dead female fetus in the 18th of pregnancy, pathological examination of the foetus confirmed the existence of trisomy 18.
羊膜穿刺术是由妊娠30周前出现的羊水过多引起的。羊水检查显示18三体综合征,甲胎蛋白值升高。曾考虑终止妊娠,但患者拒绝了。这使得能够在随后几周内监测胎儿发育情况。患者在妊娠第18周产下一名死胎女婴后,对胎儿进行的病理检查证实存在18三体综合征。