Tep P, Lamotte S, Bocquet L, Grossin M, Kahn M F, Marc A
Ann Med Interne (Paris). 1981;132(1):36-40.
A 51-year-old man presented with isolated diffuse gingival hypertrophy, the diagnosis of a plasmocytoma being suspected after pathological and immunohistological examinations of a gingival biopsy (light chain lambda plasmocytes). The isolated nature of this diffuse gingival plasmocytoma was confirmed by biological tests and radiological investigations. The evolution of solitary plasmocytomas is variable, and while certain of these lesions remain isolated even after many years, other plasmocytomas, apparently local, are associated with myelomas which either become evident or may sometimes develop. The extremely rare nature of diffuse gingival locations of extra-osseous solitary plasmocytomas is confirmed by a review of the published literature. Studying histological sections by immunofluorescence enables the polyclonal or monoclonal nature of the plasmocytes to be established, this distinction being an important element in the prognosis.
一名51岁男性出现孤立性弥漫性牙龈肥大，牙龈活检（轻链λ浆细胞）经病理和免疫组织学检查后怀疑为浆细胞瘤。生物学检测和影像学检查证实了这种弥漫性牙龈浆细胞瘤的孤立性质。孤立性浆细胞瘤的病程多变，虽然其中一些病变即使多年后仍保持孤立，但其他看似局部的浆细胞瘤与骨髓瘤相关，骨髓瘤要么变得明显，要么有时会发展。回顾已发表的文献证实了骨外孤立性浆细胞瘤弥漫性牙龈部位极为罕见。通过免疫荧光研究组织学切片能够确定浆细胞的多克隆或单克隆性质，这种区分是预后的一个重要因素。
