Natali R, Rachinel O, Corfu G, Menager G
Ann Otolaryngol Chir Cervicofac. 1980 Oct-Nov;97(10-11):889-96.
The authors studied the solitary plasmocytoma, since it would appear to pose a triple problem: diagnostic, prognostic and therapeutic. 1. From a diagnostic standpoint, histological interpretation, even by experienced histopathologists would appear to be extremely difficult since study of the course showed that in a significant number of cases a carcinoma develops, indicating that the previous diagnosis was erroneous. 2. From a prognostic standpoint, the course would appear to be extremely variable in terms of survival, this being described in both the French as well as the American literature. However, there is a wide variation in differential statistical studies with regard to mean survival periods. 3. Finally, there is a wide range of opinions concerning therapy. Certain authors adopt a surgical approach only, whilst others use radiotherapy only. Few use a combination of radiotherapy and surgery even though this would appear to be logical since it falls in line with the standard attitude of oncologists concerning solid tumours. Rather than draw any conclusions, it would appear to be desirable to follow up this study with an adequate statistical number in order to define an overall position from both a prognostic as well as therapeutic standpoint.
作者们对孤立性浆细胞瘤展开了研究，因为它似乎带来了三个问题：诊断、预后和治疗。1. 从诊断角度来看，即便由经验丰富的组织病理学家进行组织学解读，似乎也极为困难，因为病程研究显示，在相当数量的病例中会发展为癌，这表明先前的诊断有误。2. 从预后角度来看，就生存期而言，病程似乎极具变异性，法国和美国的文献中均有相关描述。然而，在平均生存期的差异统计研究方面存在很大差异。3. 最后，关于治疗存在广泛的意见分歧。某些作者仅采用手术方法，而其他作者仅使用放射疗法。很少有人将放射疗法和手术结合使用，尽管这似乎合乎逻辑，因为它与肿瘤学家对实体瘤的标准态度一致。与其得出任何结论，似乎有必要用足够的统计数量对这项研究进行跟进，以便从预后和治疗角度确定总体立场。
