前列环素（PGI2）在肺动脉高压中的血流动力学效应。
Haemodynamic effects of prostacyclin (PGI2) in pulmonary hypertension.
作者信息
Guadagni D N, Ikram H, Maslowski A H
出版信息
Br Heart J. 1981 Apr;45(4):385-8. doi: 10.1136/hrt.45.4.385.
Abstract
An infusion of prostacyclin (PGI2) in four patients with pulmonary hypertension resulted in a dose-related decrease in the systemic and pulmonary vascular resistance and an increase in cardiac output. No selectivity for the pulmonary vasculature was observed and the drug was not therapeutically beneficial.
摘要
对四名肺动脉高压患者输注前列环素（PGI2），导致体循环和肺血管阻力呈剂量相关下降，心输出量增加。未观察到对肺血管系统的选择性，且该药物无治疗益处。
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