给冈恩大鼠注射鼠血巴尔通体后，移植分离的肝细胞引发的溶血性贫血
Haemolytic anaemia in the Gunn rat following transplantation of isolated hepatocytes injected with Haemobartonella muris.
作者信息
Woods R J, Parbhoo S P
出版信息
Br J Exp Pathol. 1981 Feb;62(1):8-12.
Abstract
Extensively purified preparations of isolated rat hepatocytes derived from Wistar rats infected with Haemobartonella muris induced haemolytic anaemia when injected into congenitally jaundiced Gunn rats. In the absence of overt parasitaemia and marked falls in haematocrit, elevation of total plasma bilirubin levels was a valuable indicator of red-cell destruction. Evidence is presented that the parasite is removed by the spleen from the surface of infected red cells which then remain in the circulation.
摘要
从感染了鼠血巴尔通体的Wistar大鼠分离得到的高度纯化的大鼠肝细胞制剂，注射到先天性黄疸的Gunn大鼠体内时会诱发溶血性贫血。在没有明显寄生虫血症和血细胞比容显著下降的情况下，血浆总胆红素水平升高是红细胞破坏的一个重要指标。有证据表明，寄生虫被脾脏从受感染红细胞表面清除，这些红细胞随后仍留在循环中。
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本文引用的文献
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Lifespan of rat erythrocytes parasitized by Bartonella muris.被鼠巴尔通体寄生的大鼠红细胞的寿命
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Bartonellaceae.巴尔通体科
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Research complications due to Haemobartonella and Eperythrozoon infections in experimental animals.实验动物中由血巴尔通体和附红细胞体感染引起的研究并发症。
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