Oyama T, Taniguchi K, Takazawa T, Matsuki A, Kudo M
Can Anaesth Soc J. 1980 Nov;27(6):556-9. doi: 10.1007/BF03006885.
The effect of halothane-nitrous oxide anaesthesia and abdominal surgery on endocrine function was investigated in 18 elderly patients whose ages ranged from 65 to 77 (mean 69 years). Cortisol levels in plasma increased significantly during anaesthesia and surgery, and the increases were slightly higher than those in young adults. Plasma aldosterone increased and insulin levels did not change during the procedures, and these levels were lower than in younger adults. The endocrine responses in elderly patients were similar in magnitude to those in young adults. Therefore it appears that no special hormonal treatment is necessary for elderly patients undergoing routine surgical procedures.
对18名年龄在65至77岁（平均69岁）之间的老年患者，研究了氟烷 - 氧化亚氮麻醉和腹部手术对内分泌功能的影响。麻醉和手术期间血浆皮质醇水平显著升高，且升高幅度略高于年轻人。手术过程中血浆醛固酮升高而胰岛素水平未变，且这些水平低于年轻人。老年患者的内分泌反应在程度上与年轻人相似。因此，对于接受常规外科手术的老年患者，似乎无需进行特殊的激素治疗。
