• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Determination of human immunoglobulin M rheumatoid factor by a solid-phase radioimmunoassay which uses human immunoglobulin G in antigen-antibody complexes.通过使用抗原-抗体复合物中的人免疫球蛋白G的固相放射免疫测定法测定人免疫球蛋白M类风湿因子。
J Clin Microbiol. 1978 Aug;8(2):134-41. doi: 10.1128/jcm.8.2.134-141.1978.
2
Radioimmunoassay for IgG and IgM rheumatoid factors.IgG和IgM类风湿因子的放射免疫测定
Braz J Med Biol Res. 1986;19(3):395-401.
3
[The quantitative determination of the IgM rheumatoid factor using a solid-phase radioimmunoassay. Comparison with the agglutination test and the radioimmuno-polyethyleneglycol precipitation test].[使用固相放射免疫测定法对IgM类风湿因子进行定量测定。与凝集试验和放射免疫-聚乙二醇沉淀试验的比较]
Allerg Immunol (Leipz). 1985;31(1):45-54.
4
IgM, IgA and IgG rheumatoid factors in patients with rheumatoid arthritis and normal donors.类风湿关节炎患者和正常供体中的 IgM、IgA 和 IgG 类风湿因子。
Clin Rheumatol. 1985 Dec;4(4):392-8. doi: 10.1007/BF02031890.
5
Evaluation of six tests for circulating IgG complexes with special reference to IgM rheumatoid factors: analysis of systemic lupus erythematosus and rheumatoid arthritis series.六种循环IgG复合物检测方法的评估，特别提及IgM类风湿因子：系统性红斑狼疮和类风湿关节炎系列分析
Clin Exp Immunol. 1981 Oct;46(1):149-60.
6
[Rheumatoid factors of immunoglobulin classes IgA, IgG and IgM: methods of determination and clinical value].免疫球蛋白IgA、IgG和IgM类别的类风湿因子：检测方法及临床价值
Schweiz Med Wochenschr. 1986 Sep 20;116(38):1290-7.
7
Determination of IgE rheumatoid factor. Comparison of a solid-phase radioimmunoassay and an enzyme immunoassay.IgE类风湿因子的测定。固相放射免疫测定法与酶免疫测定法的比较。
Allerg Immunol (Leipz). 1987;33(2):101-9.
8
Relationship of serum IgG rheumatoid factor to IgM rheumatoid factor and disease activity in rheumatoid arthritis.类风湿关节炎中血清IgG类风湿因子与IgM类风湿因子及疾病活动度的关系
J Rheumatol. 1986 Apr;13(2):259-62.
9
A quantitative assay for IgA rheumatoid factor.IgA类风湿因子的定量测定
J Immunol Methods. 1982;50(1):89-98. doi: 10.1016/0022-1759(82)90306-4.
10
IgE rheumatoid factor. Occurrence and diagnostic importance in comparison with IgM rheumatoid factor and circulating immune complexes.IgE类风湿因子。与IgM类风湿因子及循环免疫复合物相比的发生率及诊断意义。
J Investig Allergol Clin Immunol. 1991 Oct;1(5):302-7.

引用本文的文献

1
Intrathecal synthesis of virus antibodies in multiple sclerosis patients.多发性硬化症患者鞘内病毒抗体的合成
Infect Immun. 1982 Nov;38(2):399-407. doi: 10.1128/iai.38.2.399-407.1982.
2
Comparison of nonspecific reactivity in indirect and reverse immunoassays for measles and mumps immunoglobulin M antibodies.麻疹和腮腺炎免疫球蛋白M抗体间接和反向免疫测定中非特异性反应性的比较。
J Clin Microbiol. 1984 Nov;20(5):972-6. doi: 10.1128/jcm.20.5.972-976.1984.
3
Subcellular fractions in rubella immunoassays.风疹免疫测定中的亚细胞组分。
Eur J Clin Microbiol. 1984 Feb;3(1):19-24. doi: 10.1007/BF02032809.
4
Detection of IgM antibodies to measles virus by enzyme-immunoassay.采用酶免疫测定法检测麻疹病毒IgM抗体。
Med Microbiol Immunol. 1983;171(4):187-98. doi: 10.1007/BF02123492.
5
[A rapid method for the determination of virus-specific IgM antibodies].[一种测定病毒特异性IgM抗体的快速方法]
Infection. 1982 Sep-Oct;10(5):267-70. doi: 10.1007/BF01640871.
6
Enzyme immunoassays for measurement of cytomegalovirus immunoglobulin M antibody.用于检测巨细胞病毒免疫球蛋白M抗体的酶免疫测定法。
J Clin Microbiol. 1981 Oct;14(4):427-32. doi: 10.1128/jcm.14.4.427-432.1981.
7
Sensitivity and specificity of viral immunoglobulin M determination by indirect enzyme-linked immunosorbent assay.间接酶联免疫吸附测定法检测病毒免疫球蛋白M的敏感性和特异性
J Clin Microbiol. 1988 Feb;26(2):328-32. doi: 10.1128/jcm.26.2.328-332.1988.
8
Elimination of nonspecific cytomegalovirus immunoglobulin M activities in the enzyme-linked immunosorbent assay by using anti-human immunoglobulin G.通过使用抗人免疫球蛋白G消除酶联免疫吸附测定中巨细胞病毒非特异性免疫球蛋白M活性。
J Clin Microbiol. 1986 Mar;23(3):576-81. doi: 10.1128/jcm.23.3.576-581.1986.
9
Solid-phase radioimmunoassay of serum immunoglobulin A antibodies to respiratory syncytial virus and adenovirus.血清中呼吸道合胞病毒和腺病毒免疫球蛋白A抗体的固相放射免疫测定
J Clin Microbiol. 1979 Aug;10(2):192-7. doi: 10.1128/jcm.10.2.192-197.1979.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Preparation of iodine-131 labelled human growth hormone of high specific activity.高比活度碘-131标记人生长激素的制备
Nature. 1962 May 5;194:495-6. doi: 10.1038/194495a0.
3
THE RHEUMATOID FACTOR IN DEFINITE RHEUMATOID ARTHRITIS. AN ANALYSIS OF 1279 ADULT PATIENTS, WITH A FOLLOW-UP STUDY.确诊类风湿关节炎中的类风湿因子。1279例成年患者分析及随访研究
Acta Rheumatol Scand Suppl. 1965:SUPPL 9:1-121. doi: 10.3109/rhe1.1965.10.suppl-9.01.
4
The problem of the antibody nature of the rheumatoid factor.类风湿因子的抗体性质问题。
Ann Med Exp Biol Fenn. 1961;39 (Suppl 7):1-60.
5
Relation between Gm types and hemagglutinating substances in rheumatoid sera.类风湿血清中Gm类型与血凝物质的关系。
Acta Pathol Microbiol Scand. 1960;50:89-105. doi: 10.1111/j.1699-0463.1960.tb01175.x.
6
1958 REVISION of diagnostic criteria for rheumatoid arthritis.1958年类风湿性关节炎诊断标准修订版。
Arthritis Rheum. 1959 Feb;2(1):16-20. doi: 10.1002/1529-0131(195902)2:1<16::aid-art1780020104>3.0.co;2-9.
7
Use of anti-Rh sera for demonstrating agglutination activating factor in rheumatoid arthritis.使用抗Rh血清来证明类风湿性关节炎中的凝集激活因子。
Proc Soc Exp Biol Med. 1956 May;92(1):198-200. doi: 10.3181/00379727-92-22426.
8
Radioimmunoassay of rheumatoid factor.类风湿因子的放射免疫测定
Arthritis Rheum. 1969 Oct;12(5):483-90. doi: 10.1002/art.1780120504.
9
Kinetics of the respiratory syncytial virus growth cycle in HeLa cells.呼吸道合胞病毒在HeLa细胞中的生长周期动力学
Arch Gesamte Virusforsch. 1969;28(2):122-32. doi: 10.1007/BF01249378.
10
Studies of radioiodinated fibrinogen. I. Physicochemical properties of the ICl, chloramine-T, and electrolytic reaction products.放射性碘化纤维蛋白原的研究。I. 碘氯、氯胺-T及电解反应产物的物理化学性质。
Biochim Biophys Acta. 1972 Dec 28;285(2):404-13. doi: 10.1016/0005-2795(72)90327-3.

通过使用抗原-抗体复合物中的人免疫球蛋白G的固相放射免疫测定法测定人免疫球蛋白M类风湿因子。

Determination of human immunoglobulin M rheumatoid factor by a solid-phase radioimmunoassay which uses human immunoglobulin G in antigen-antibody complexes.

作者信息

Ziola B, Meurman O, Matikainen M T, Salmi A, Kalliomäki J L

出版信息

J Clin Microbiol. 1978 Aug;8(2):134-41. doi: 10.1128/jcm.8.2.134-141.1978.

DOI:10.1128/jcm.8.2.134-141.1978
PMID:701459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC275170/
Abstract

A solid-phase radioimmunoassay for the rapid determination of human immunoglobulin M (IgM) rheumatoid factor (RF) has been developed. Preparation of the solid phase for the assay involved the formation of complexes between respiratory syncytial virus-specific human IgG antibodies and virus antigen on the surface of polystyrene balls. Binding of serum RF to IgG in the immune complex was subsequently detected by 125I-labeled mu-chain-specific antibodies to human IgM. The amount of radioactive indicator antibody bound was converted to units of RF by comparison to the standard curve for an RF reference-serum pool. This assay should prove useful in studies of the physiological role of RF, since it can effectively measure low levels of circulating RF.

摘要

已开发出一种用于快速测定人免疫球蛋白M（IgM）类风湿因子（RF）的固相放射免疫测定法。该测定法的固相制备涉及呼吸道合胞病毒特异性人IgG抗体与聚苯乙烯球表面病毒抗原之间形成复合物。随后通过125I标记的人IgMμ链特异性抗体检测血清RF与免疫复合物中IgG的结合。通过与RF参考血清库的标准曲线比较，将结合的放射性指示抗体量换算为RF单位。该测定法在RF生理作用的研究中应会证明有用，因为它能有效测量循环中低水平的RF。