Ducastelle T, Reynes M, Diebold J
Pathol Biol (Paris). 1981 Feb;29(2):111-25.
Peripheral lymphoid organs have two groups of non lymphoid cells : that of macrophages which belongs to R. van Furth's system of mononuclear phagocytes and the one made of elements for long labelled "reticular cells". The use of electron microscopy has permitted a good understanding of these elements and a recognition of ubiquitary cells (fibroblasts, endothelial cells) and specific cells to the lymph node which seem to play a very important role in the immune reactions (interdigitated cells, reticulum cells, dendritic cells). We describe their light and electron microscopical features and histoenzymatic characters, and present the actual concept of their origin and function. The latest discoveries on their classification are reviewed and have permitted to distinguish three categories of non lymphoid cells : first the group of reticulum cells (reticulum cells and dendritic cells), second that of mononuclear phagocytes (macrophages and interdigitated cells) and third that of endothelial cells. Other elements of questionable existence or insufficiently known do not appear in this classification : dark cells, Steinman and Cohn's dendritic cells and cells containing Birbeck's granules.
一类是巨噬细胞，属于范·富思的单核吞噬细胞系统；另一类由长期以来被标记为“网状细胞”的成分组成。电子显微镜的应用使人们对这些成分有了很好的理解，并识别出了普遍存在的细胞（成纤维细胞、内皮细胞）以及淋巴结特有的细胞，这些细胞似乎在免疫反应中起着非常重要的作用（交错突细胞、网状细胞、树突状细胞）。我们描述了它们的光镜和电镜特征以及组织酶学特性，并介绍了它们起源和功能的实际概念。对它们分类的最新发现进行了综述，从而区分出三类非淋巴细胞：第一类是网状细胞（网状细胞和树突状细胞），第二类是单核吞噬细胞（巨噬细胞和交错突细胞），第三类是内皮细胞。其他存在疑问或了解不足的成分未出现在该分类中：暗细胞、斯坦曼和科恩的树突状细胞以及含有伯贝克颗粒的细胞。
