Kato Y, Shiraki S, Hamada Y, Iyehara-Ogawa H, Nakayama H
Can J Microbiol. 1980 Dec;26(12):1518-22. doi: 10.1139/m80-254.
The effects of postirradiation incubation with various chemicals structurally related to pantolactone on the survival of ultraviolet-irradiated Escherichia coli lon and ruv mutants were examined. Certain cyclic compounds with a butyrolactone, tetrahydrofuran, furan, tetrahydropyran, or 2-pyron ring showed substantial rescue activity in lon and (or) ruv mutants. In addition, several aliphatic, monocarboxylic acid salts, including hydrolysis products from pantolactone and butyrolactone, were also active in one or both of these mutants, especially pantoate and other hydroxy acid salts in the ruv bacterium. The two mutants differed considerably in their susceptibility spectra for the rescue actions of these compounds.
研究了用与泛内酯结构相关的各种化学物质进行辐照后孵育对紫外线照射的大肠杆菌lon和ruv突变体存活的影响。某些具有丁内酯、四氢呋喃、呋喃、四氢吡喃或2-吡喃环的环状化合物在lon和（或）ruv突变体中表现出显著的拯救活性。此外，几种脂肪族一元羧酸盐，包括泛内酯和丁内酯的水解产物，在这两种突变体中的一种或两种中也具有活性，特别是ruv细菌中的泛酸盐和其他羟酸盐。这两种突变体对这些化合物拯救作用的敏感谱有很大差异。
