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用于犬特应性疾病诊断的放射变应原吸附试验

The radioallergosorbent test in the diagnosis of canine atopic disease.

作者信息

Halliwell R E, Kunkle G A

出版信息

J Allergy Clin Immunol. 1978 Oct;62(4):236-42. doi: 10.1016/0091-6749(78)90213-0.

DOI:10.1016/0091-6749(78)90213-0
PMID:701658
Abstract

The radioallergosorbent test (RAST) was adapted for use in the dog employing purified anti-canine IgE. The agreement between positive RAST and positive skin test ranged from 82% for ragweed to only 12.5% for dandelion. Agreement between negative tests in the case of all allergens was 100%. Further developmental studies of canine RAST are warranted in view of the value of the dog as an experimental model of atopic disease.

摘要

放射变应原吸附试验(RAST)经改良后,采用纯化的抗犬IgE用于犬类。阳性RAST与阳性皮肤试验之间的一致性,从豚草的82%到蒲公英的仅12.5%不等。所有过敏原阴性试验之间的一致性为100%。鉴于犬作为特应性疾病实验模型的价值,有必要对犬RAST进行进一步的深入研究。

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The radioallergosorbent test in the diagnosis of canine atopic disease.用于犬特应性疾病诊断的放射变应原吸附试验
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引用本文的文献

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Experimental models of asthma.哮喘的实验模型。
Lung. 1982;160(5):231-43. doi: 10.1007/BF02719297.
2
Allergen specific IgGd antibodies in dogs with atopic dermatitis as determined by the enzyme linked immunosorbent assay (ELISA).通过酶联免疫吸附测定(ELISA)测定特应性皮炎犬的变应原特异性IgD抗体。
Clin Exp Immunol. 1985 Feb;59(2):359-63.
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Induction of non-IgE anaphylactic antibodies in dogs.犬非IgE过敏性抗体的诱导
Clin Exp Immunol. 1985 Feb;59(2):351-8.