Spratt S K, Ginsburgh C L, Nunn W D
J Bacteriol. 1981 Jun;146(3):1166-9. doi: 10.1128/jb.146.3.1166-1169.1981.
Escherichia coli mutants defective in propionate metabolism (Prp-) were isolated after mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine. Prp- mutants demonstrate a phenotypic inability to grow on odd-chain-length fatty acids. The new genetic locus for the Prp- phenotype maps at approximately 98 min on the E. coli chromosome.
在用N-甲基-N'-硝基-N-亚硝基胍诱变后,分离出了丙酸代谢缺陷型(Prp-)的大肠杆菌突变体。Prp-突变体表现出在奇数链长脂肪酸上无法生长的表型。Prp-表型的新基因座位于大肠杆菌染色体上约98分钟处。