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[瓜西他酯治疗慢性支气管炎的初步研究]

[Preliminary study of guacetisal in chronic bronchitis].

作者信息

Marvulli G, Partipilo N

出版信息

Minerva Med. 1981 Feb 28;72(7):409-16.

PMID:7017492
Abstract

A single-blind, between-patients trial was run on two randomly formed groups of 15 hospitalised male patients with chronic obstructive bronchitis, carefully selected to rule out excessive interference on the part of other pathologies or lund complications, in which 3 tablespoonfuls a day Broncaspin suspension were compared with the same dose of a recognised commercial preparation composed by sodium thymosulphonate, ammonium acetate, codeine, and tincture of datura. The clinical and instrumental data showed that Broncaspin had greater therapeutic activity. The local and general tolerability of the two preparations was uneceptionable.

摘要

对两组随机形成的各15名住院男性慢性阻塞性支气管炎患者进行了一项单盲、患者间试验。患者经过精心挑选,以排除其他病理状况或肺部并发症的过度干扰。试验中,将每天服用3汤匙的溴己新悬浮液与相同剂量的一种由硫代胸腺嘧啶钠、醋酸铵、可待因和曼陀罗酊组成的知名市售制剂进行比较。临床和仪器数据表明,溴己新具有更强的治疗活性。两种制剂的局部和总体耐受性都很好。

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