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麻疹、腮腺炎和风疹(HPV-77:DE-5和RA 27/3)病毒疫苗单独及联合使用的临床和血清学评估。

Clinical and serologic evaluation of measles, mumps, and rubella (HPV-77:DE-5 and RA 27/3) virus vaccines, singly and in combination.

作者信息

Lerman S J, Bollinger M, Brunken J M

出版信息

Pediatrics. 1981 Jul;68(1):18-22.

PMID:7017582
Abstract

A double-blind, placebo-controlled comparison of single component and combination measles, mumps, and rubella (HPV-77:DE-5 and RA 27/3) virus vaccines involving 502 young children was conducted. The rubella antibody response was similar with RA 27/3 rubella and measles-mumps-rubella (RA 27/3) vaccines, but was diminished with the combination vaccine that incorporated HPV-77:DE-5 rubella. There was no evidence of enhanced clinical reactivity with either of the measles-mumps-rubella vaccines.

摘要

对502名幼儿进行了一项双盲、安慰剂对照的单组分和联合麻疹、腮腺炎和风疹(HPV-77:DE-5和RA 27/3)病毒疫苗比较研究。RA 27/3风疹疫苗和麻疹-腮腺炎-风疹(RA 27/3)疫苗的风疹抗体反应相似,但含有HPV-77:DE-5风疹的联合疫苗的抗体反应有所减弱。没有证据表明这两种麻疹-腮腺炎-风疹疫苗会增强临床反应性。

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