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接受维持性血液透析治疗的胰岛素依赖型糖尿病患者的视觉功能可以得到保留。

Visual function can be preserved in insulin-dependent diabetic patients treated by maintenance haemodialysis.

作者信息

El Shahat Y, Rottembourg J, Bellio P, Guimont M C, Rousselie F, Jacobs C

出版信息

Proc Eur Dial Transplant Assoc. 1980;17:167-72.

PMID:7017675
Abstract

Evolution of visual function was assessed in 43 insulin-dependent diabetic (IDD) patients treated by maintenance haemodialysis (MH) for a cumulative duration of 1248 patient-months. At start of MH, 23 patients (46 eyes) still had good vision, 20 patients (40 eyes) were blind. All 40 blind eyes had severe proliferative retinopathy (PR) with additional irreversible complications in 32. Of the 46 eyes with preserved vision, PR was present in 24 (52.2%) with only 2 additional severe complications. Restoration of sight was obtained either spontaneously or after ophthalmic surgery in 6 eyes (7%). Stabilisation was achieved in 74% of eyes which retained vision at the start of MH. Two patients with eyesight at start of MH became blind (8.7%). Aggravation of visual function is mainly related to development of PR and not to haemodialysis per se. Careful ophthalmic follow-up, together with close control of diabetes, blood-pressure and uraemia can ensure preservation of vision in most IDD patients treated by MH.

摘要

对43例接受维持性血液透析(MH)治疗累计时长为1248患者月的胰岛素依赖型糖尿病(IDD)患者的视觉功能演变情况进行了评估。在开始MH治疗时,23例患者(46只眼)视力尚好,20例患者(40只眼)失明。所有40只失明眼中均有严重的增殖性视网膜病变(PR),其中32只眼还伴有其他不可逆并发症。在46只视力保留的眼中,24只眼(52.2%)存在PR,仅2只眼伴有其他严重并发症。6只眼(7%)视力自发恢复或经眼科手术后恢复。在开始MH治疗时视力保留的眼中,74%实现了视力稳定。2例在开始MH治疗时有视力的患者失明(8.7%)。视觉功能恶化主要与PR的进展有关,而非与血液透析本身相关。仔细的眼科随访,以及对糖尿病、血压和尿毒症的密切控制,可确保大多数接受MH治疗的IDD患者的视力得以保留。

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