Coppo R, Roccatello D, Aprato A, Basolo B, Camussi G, Messina M, Bulzomi M R, Segoloni G, Giachino G, Piccoli G B, Vercellone A, Piccoli G
Arch Sci Med (Torino). 1981 Apr-Jun;138(2):161-74.
The application of tests for the determination of serum immune complexes in nephrology has supplied fresh pathogenetic and symptomatological information. An account is given of results obtained in primary and secondary glomerulonephritis using four methods; the solid-phase Clq test, the polyethylene glycol precipitation test, the immunofluorescence on polymorphonucleates tests, and the solid-phase conglutinins test (with anti-IgA antibodies). The results take on a symptomatological meaning in many classes of human glomerulonephritis, both in the differentiation of primary forms and those secondary to systemic diseases, and in prognosis. A critical review is made of the data obtained in a personal series in the light of a long-term follow-up. The limits and specificity of each test are also discussed.
血清免疫复合物测定试验在肾脏病学中的应用提供了新的发病机制和症状学信息。本文介绍了使用四种方法在原发性和继发性肾小球肾炎中获得的结果；固相Clq试验、聚乙二醇沉淀试验、多形核白细胞免疫荧光试验和固相凝集素试验（使用抗IgA抗体）。这些结果在许多类型的人类肾小球肾炎中具有症状学意义，无论是在原发性形式与继发于全身性疾病的形式的鉴别中，还是在预后判断中。根据长期随访对个人系列中获得的数据进行了批判性综述。还讨论了每种试验的局限性和特异性。
