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[骨髓移植中的细胞遗传学。II. 急性淋巴细胞白血病]

[Cytogenetics in bone marrow transplantations. II. Acute lymphocytic leukemia].

作者信息

Palka G, Geraci L, Felaco M, Caramelli E, Santi P, Honora B, Antonucci A

出版信息

Boll Soc Ital Biol Sper. 1981 Jan 15;57(1):27-32.

PMID:7018520
Abstract

In this we report cytogenetic data concerning two patients with Acute Lymphoblastic Leukemia (ALL), submitted to bone marrow transplantation. In one of two patients the chimere was present while in the other case it was absent, since the donor and the acceptor were of the same sex. However even in the latter case, the cytogenetic analysis was useful and led to the identification of endomitosis and endoreduplication phenomena, which are signs for an unlucky prognosis.

摘要

在此我们报告了两名接受骨髓移植的急性淋巴细胞白血病(ALL)患者的细胞遗传学数据。在这两名患者中,一名出现了嵌合体,而另一名未出现,因为供体和受体为同性。然而,即使在后一种情况下,细胞遗传学分析也很有用,并且导致了核内有丝分裂和核内复制现象的识别,这些现象是预后不良的迹象。

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