Mubarak S J, Carroll N C
Clin Orthop Relat Res. 1981 Jun(157):200-11.
Of 73 patients in whom 122 lesions of osteochondritis dissecans of the knee developed, nearly half had multiple lesions and 30% were of short stature. Endogenous and exogenous traumas play a minor role in the etiology of this disorder. Over half of the children with a history of trauma had bilateral and symmetrical lesions. Constitutional factors, such as hereditary predisposition, endocrine dysfunction, collagen and epiphyseal abnormalities, are frequently associated with juvenile osteochondritis dissecans of the knee.
在73例发生膝关节剥脱性骨软骨炎122处病变的患者中，近半数有多处病变，30%身材矮小。内源性和外源性创伤在该疾病的病因中起次要作用。有创伤史的儿童中，超过半数有双侧对称性病变。体质因素，如遗传易感性、内分泌功能障碍、胶原和骨骺异常，常与青少年膝关节剥脱性骨软骨炎相关。
