Milgram J W
Radiology. 1978 Feb;126(2):305-11. doi: 10.1148/126.2.305.
The specimens from 50 operated cases of osteochondritis dissecans of the distal femur were analyzed histopathologically. Radiodensity of the specimens of osteochondritis dissecans was due (a) attached subchondral bone, (b) degenerative secondary calcification of articular cartilage, (c) revascularization with new bone, and, in the free bodies, (d) calcification in new surface layers of cartilage and bone. The pathological findings in the specimens suggested an etiology from trauma rather than avascular necrosis. Half of the specimens of osteochondritis dissecans contained no subchondral bone but only articular cartilage. It was postulated that the relationship of the attached lesions to the intercondylar notch of the femur, which permitted a partially retained blood supply, created a spectrum of different histopathological changes in the subchondral bone of those specimens with attached bone.
对50例股骨远端剥脱性骨软骨炎手术病例的标本进行了组织病理学分析。剥脱性骨软骨炎标本的放射密度归因于：(a) 附着的软骨下骨；(b) 关节软骨的退行性继发性钙化；(c) 新生骨的血管再生；以及在游离体中，(d) 软骨和骨新表层的钙化。标本的病理结果提示病因是创伤而非缺血性坏死。一半的剥脱性骨软骨炎标本不含软骨下骨，仅含关节软骨。据推测，附着病变与股骨髁间切迹的关系（这种关系允许部分保留血供）在那些有附着骨的标本的软骨下骨中产生了一系列不同的组织病理学变化。
