Sams W M
Postgrad Med. 1981 Aug;70(2):193-200. doi: 10.1080/00325481.1981.11715836.
Allergic vasculitis presents with purpuric lesions that are distinguishable by their palpability and by their distribution primarily on the lower extremities. The disease can affect any organ system but most often involves the kidneys, joints, gastrointestinal tract, lungs, or nervous system. Histopathologic examination shows characteristic destruction of the vessel wall by polymorphonuclear leukocytes. Numerous etiologic agents have been implicated, but streptococcal infection and drug ingestion are the most common. Presumptive evidence suggests that the disease is due to immune complexes. The workup is aimed at establishing the cause and extent of systemic involvement, and treatment is tailored accordingly.
变应性血管炎表现为紫癜性损害，可通过触诊以及主要分布于下肢的特点来鉴别。该疾病可累及任何器官系统，但最常累及肾脏、关节、胃肠道、肺或神经系统。组织病理学检查显示多形核白细胞对血管壁的特征性破坏。许多病因已被提及，但链球菌感染和药物摄入最为常见。初步证据表明该疾病是由免疫复合物引起的。检查旨在确定全身受累的原因和程度，并据此进行相应治疗。
