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在一般医疗实践中,对噻洛芬酸和阿司匹林治疗肌肉风湿病、纤维织炎、扭伤及软组织损伤进行的双盲对照研究。

A comparative double-blind study of tiaprofenic acid and aspirin in the treatment of muscular rheumatism, fibrositis, sprains and soft tissue injuries in general practice.

作者信息

Donald J F, Molla A L

出版信息

J Int Med Res. 1980;8(6):382-7. doi: 10.1177/030006058000800602.

DOI:10.1177/030006058000800602
PMID:6969194
Abstract

Analgesic and anti-inflammatory properties of tiaprofenic acid 200 mg t.d.s. were compared with those of aspirin 600 mg t.d.s. in 100 patients in general practice suffering from muscular rheumatic pain, fibrositis, sprains and soft tissue injuries. Tiaprofenic acid was shown to be better than aspirin in relieving pain by clinical assessment although both drugs were equally effective according to patients daily assessment. It was not possible to demonstrate any anti-inflammatory action by reduction of swelling, but this was only present in 20% of patients initially. Side-effects, none serious, were similar in both groups.

摘要

对100名患有肌肉风湿性疼痛、纤维织炎、扭伤和软组织损伤的全科门诊患者,比较了每日三次服用200毫克噻洛芬酸与每日三次服用600毫克阿司匹林的镇痛和抗炎特性。通过临床评估显示,噻洛芬酸在缓解疼痛方面优于阿司匹林,不过根据患者的每日评估,两种药物的效果相当。未能通过肿胀减轻来证明有任何抗炎作用,但最初只有20%的患者存在肿胀。两组的副作用均不严重,且相似。

相似文献

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A comparative double-blind study of tiaprofenic acid and aspirin in the treatment of muscular rheumatism, fibrositis, sprains and soft tissue injuries in general practice.在一般医疗实践中,对噻洛芬酸和阿司匹林治疗肌肉风湿病、纤维织炎、扭伤及软组织损伤进行的双盲对照研究。
J Int Med Res. 1980;8(6):382-7. doi: 10.1177/030006058000800602.
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Tiaprofenic acid. A review of its pharmacological properties and therapeutic efficacy in rheumatic diseases and pain states.噻洛芬酸。对其在风湿性疾病和疼痛状态下的药理特性及治疗效果的综述。
Drugs. 1985 Mar;29(3):208-35. doi: 10.2165/00003495-198529030-00002.