Ruiz A, Bulmer G S
Appl Environ Microbiol. 1981 May;41(5):1225-9. doi: 10.1128/aem.41.5.1225-1229.1981.
Nearly 10(6) cells of Cryptococcus neoformans were cultured per g of pigeon droppings in a vacant tower. The air in the tower contained an average of 45 viable cells of C. neoformans per 100 liters: 60% of the cells were less than 4.7 micron in diameter. It is estimated that a human exposed to this atmosphere for 1 h would have 41 cells of c. neoformans deposited in the lungs. Sweeping resulted in the aerosolization of large numbers of cells of C. neoformans from 4.7 to 11 micron in diameter, the number of cells less than 4.7 micron remained relatively constant. One minute after sweeping, 4.4% of viable airborne cells of C. neoformans were less than 1.1 micron in diameter. We believe that this is the first report of isolating such small cells of C. neoformans from a natural site.
在一座空塔楼中,每克鸽粪培养出近10⁶个新型隐球菌细胞。塔楼空气中每100升平均含有45个活的新型隐球菌细胞:60%的细胞直径小于4.7微米。据估计,人类暴露于这种环境1小时,肺部会沉积41个新型隐球菌细胞。清扫导致大量直径为4.7至11微米的新型隐球菌细胞形成气溶胶,直径小于4.7微米的细胞数量保持相对稳定。清扫1分钟后,直径小于1.1微米的活的空气传播新型隐球菌细胞占4.4%。我们认为这是首次从自然环境中分离出如此小的新型隐球菌细胞的报告。